On March 19-20th 2020 the EBRA Spring school on Open Research in collaboration with the QUEST Institute Berlin was conducted as online conference. 22 participants attended the virtual meeting and discussed the presentations. From ‘Quality and Robustness in Biomedical Research’ via ‘Experimental Design (Strategies against Biases, Exploration to Confirmation)’, and ‘What is N? Experimental, observational, and measurement units’ to ‘Statistics and p-value’ the lectures detailed a tremendous amount of information and support for experimental preclinical research. The attendees honored the online workshop with specific questions also in regard to own projects. Originally planned as physical conference the Corona pandemic necessitated an alternative approach and EBRA highly appreciates the effort taken by our collaboration partner. Consecutive events are intended for 2021.